Spread across an 82-acre campus, Knox College has 45 academic and residential buildings. The Andrew Fitness Center, a 13,000 sq ft facility features state-of-the-art equipment and is significantly larger than the former fitness center. The centerpiece of the campus is Old Main, a national historic landmark. The Seymour library was ranked 3rd best library in the nation by the Princeton Review. It houses 350,000 books and more than 14,000 periodicals. It has six new academic centers namely The center for career and pre-professional development, the center for advanced studies, global studies, community service, and intercultural life.